MECANISMOS DE RESISTÊNCIA AOS ANTIBIÓTICOS BETALACTÂMICOS PELOS STAPHYLOCOCCUS AUREUS

Lohraine Talia  Domingues; Mariana Kely Diniz Gomes De  Lima; Paulo Schumann  Neto; Isabela Reis  Manzoli; Diego Bezerra  Soares

doi:10.51161/rems/1446

MECANISMOS DE RESISTÊNCIA AOS ANTIBIÓTICOS BETALACTÂMICOS PELOS STAPHYLOCOCCUS AUREUS

Autores

Lohraine Talia Domingues
Mariana Kely Diniz Gomes De Lima
Paulo Schumann Neto
Isabela Reis Manzoli
Diego Bezerra Soares

DOI:

https://doi.org/10.51161/rems/1446

Palavras-chave:

ANTIBIÓTICOS BETALACTÂMICOS, RESISTÊNCIA, STAPHYLOCOCCUS AUREUS

Resumo

Introdução: A bactéria Staphylococcus aureus é uma das mais perigosas infecções estafilocócicas resistentes a antibióticos, sobretudo porque possui alta capacidade de virulência, liberação de toxinas e conseguem se disseminar rapidamente nas regiões cutâneas, pulmonares, válvulas cardíacas e ósseas. Ademais, essas bactérias são classificadas como gram-positivas, em forma de esferas (cocos) que podem provocar espinhas e furúnculos, inclusive acometimentos mais graves, como pneumonia, meningite, endocardite, síndrome do choque tóxico e septicemia. Objetivos: Devido a elevada prevalência no número de casos e a resistência aos antibióticos betalactâmicos essa doença pode ser considerada de grande relevância ao estudo médico. Nesse contexto, são necessários mais estudos que esclareçam a padronização dessa patologia. Com isso, foi levantado a seguinte problemática: “Quais seriam os mecanismos de resistência aos antibióticos betalactâmicos pelos Staphylococcus aureus?”. Material e Métodos: A pesquisa consiste em uma revisão de literatura retrospectiva, com o objetivo de entender os aspectos de resistência aos antibióticos betalactâmicos pelos Staphylococcus aureus. Resultados: A partir desse estudo foi possível observar que as bactérias por meio da alta capacidade de replicação, conseguiram produzir algumas enzimas e estruturas que conferem um fator de resistência aos antibióticos, tais como: aderência, a cápsula de ácido hialurônico, a proteína M e outras enzimas. Nesse sentido, a enzima que mais se destaca é a betalactamase que é capaz de inibir a ação dos antibióticos betalactâmicos favorecendo ainda mais a patogenicidade durante a infecção. Conclusão: Por meio desse estudo, observou-se acentuada resistência bacteriana do Staphylococcus aureus através da capacidade de produzir enzimas principalmente a betalactamase responsável pelo fator de inviabilização dos antibióticos betalactâmicos.

Publicado

2021-07-28

Como Citar

Domingues, L. T. ., Lima, M. K. D. G. D. ., Neto, P. S. ., Manzoli, I. R., & Soares, D. B. . (2021). MECANISMOS DE RESISTÊNCIA AOS ANTIBIÓTICOS BETALACTÂMICOS PELOS STAPHYLOCOCCUS AUREUS. Revista Multidisciplinar Em Saúde, 2(3), 44. https://doi.org/10.51161/rems/1446

Baixar Citação

Edição

v. 2 n. 3 (2021)

Seção

II Congresso Brasileiro de Saúde On-line

Licença

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

O conteúdo desta revista foi migrado para https://editoraintegrar.com.br

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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Paulo Schumann Neto, Lohraine Talia Domingues, Isabela Reis Manzoli, Mariana Kely Diniz Gomes De Lima, Diego Bezerra Soares, PATOGENICIDADE DAS ESPÉCIES VIVAX E FALCIPARUM NO AGRAVAMENTO DA MALÁRIA , Revista Multidisciplinar em Saúde: v. 2 n. 3 (2021)
Diego Bezerra Soares , Isabela Reis Manzoli, Lohraine Talia Domingues, Paulo Schumann Neto, Mariana Kely Diniz Gomes De Lima, ASPECTOS IMUNOLÓGICOS DE PATOGENICIDADE DA LEISHMANIOSE TEGUMENTAR AMERICANA CUTÂNEA , Revista Multidisciplinar em Saúde: v. 2 n. 3 (2021)
Gabriele Pereira dos Reis, Diego Bezerra Soares, Isabela Reis Manzoli, Lohraine Talia Domingues, MECANISMOS BIOMOLECULARES DA SUCCINILCOLINA NA HIPERTERMIA MALIGNA , Revista Multidisciplinar em Saúde: v. 2 n. 4 (2021)
Mariana Barbosa Lopes, Diego Bezerra Soares, Gabriele Pereira Dos Reis, Fabiola Julianne Alves De Pinho, Isabela Reis Manzoli, PARACOCCIDIOIDOMICOSE: DESAFIOS PARA O ENFRENTAMENTO DE UMA DOENÇA NEGLIGENCIADA , Revista Multidisciplinar em Saúde: v. 2 n. 4 (2021)

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