O ESTRESSE E SUA INFLUÊNCIA NO DESENVOLVIMENTO E EXACERBAÇÃO DE DOENÇAS AUTOIMUNES

Edivan Lourenço Da Silva Júnior; Luisa Fernanda Camacho Gonzalez

doi:10.51161/rems/956

O ESTRESSE E SUA INFLUÊNCIA NO DESENVOLVIMENTO E EXACERBAÇÃO DE DOENÇAS AUTOIMUNES

Autores

Edivan Lourenço Da Silva Júnior
Luisa Fernanda Camacho Gonzalez

DOI:

https://doi.org/10.51161/rems/956

Palavras-chave:

Estresse, Doenças Autoimunes, Distúrbios Psicológicos, Imunologia

Resumo

Introdução: O estresse, desde o ponto de vista biológico, consiste em uma reação psicofisiológica do organismo na qual constata-se, por diferentes fatores, a alteração da homeostase, mecanismo de regulação hormonal. Este transtorno afeta cerca de noventa por cento da população mundial e, em sua forma crônica, há o desencadeamento tanto de patologias físicas como transtornos psíquicos. Objetivo: Analisar o fenômeno do estresse, desde o ponto de vista psicobiológico, e sua relação com o desenvolvimento e exacerbação de doenças autoimunes. Metodologia: Foi realizado um levantamento bibliográfico sobre a temática abordada através de consulta nas bases de dados científicos Scielo, PubMed, LILACS e Google Acadêmico, tendo como critério de inclusão publicações de artigos científicos dos últimos cinco anos. Resultados e discussão: As doenças autoimunes são alterações biológicas decorrentes da combinação de elementos que envolvem a genética, epigenética e fatores ambientais. Entre estes destaca-se o estresse psicológico, desencadeado por eventos que provocam ansiedade, pela predisposição genética, por mecanismos de enfrentamento e suporte social e também por tipos de personalidade. Além disso, este transtorno constitui um fator de risco para o tabagismo, alcoolismo, entre outros comportamentos deletérios para a saúde física e mental. Ademais, e estresse facilita o surgimento de diversas doenças metabólicas, emocionais e crônicas como o lúpus eritematoso sistêmico, a diabetes e a psoríase, deprimindo o sistema imunitário, especialmente o linfócito T auxiliar, através da ação do hormônio cortisol, sendo este responsável pelo imunossupressão através da ação das interleucinas. Conclusão: Constatou-se na literatura existente a presença de mecanismos cognitivos e sensoriais, que afetam a adaptação do organismo a estímulos agressores, característicos das situações de estresse, os quais constituem fatores de risco tanto para o desenvolvimento de doenças autoimunes, como para desestabilização do sistema imunitário. Não obstante, é necessário um maior número de estudos dentro desta temática, com vista a explorar os diferentes aspectos da correlação entre o estresse e o surgimento destas enfermidades.

Publicado

2021-04-24

Como Citar

Júnior, E. L. D. S., & Gonzalez, L. F. C. (2021). O ESTRESSE E SUA INFLUÊNCIA NO DESENVOLVIMENTO E EXACERBAÇÃO DE DOENÇAS AUTOIMUNES. Revista Multidisciplinar Em Saúde, 2(2), 16. https://doi.org/10.51161/rems/956

Baixar Citação

Edição

v. 2 n. 2 (2021): Edição Especial: Anais de Eventos

Seção

Anais do Congresso Brasileiro de Imunologia On-line

Licença

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

O conteúdo desta revista foi migrado para https://editoraintegrar.com.br

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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