O EFEITO PLACEBO E SUAS IMPLICAÇÕES NOS TRATAMENTOS MEDICAMENTOSOS

Edivan Lourenço da  Silva Júnior; Luisa Fernanda Camacho  Gonzalez

doi:10.51161/rems/1418

O EFEITO PLACEBO E SUAS IMPLICAÇÕES NOS TRATAMENTOS MEDICAMENTOSOS

Autores

Edivan Lourenço da Silva Júnior
Luisa Fernanda Camacho Gonzalez

DOI:

https://doi.org/10.51161/rems/1418

Palavras-chave:

SAÚDE FÍSICA E MENTAL, FENÔMENOS PSICOLÓGICOS, USO DE MEDICAMENTOS

Resumo

Introdução: O efeito placebo constitui uma resposta psicobiológica relacionada a processos neurofisiológicos, cujo mecanismo de ação ainda é desconhecido. Esta reação pode ser desencadeada por múltiplos fatores, atribuídos pelos pacientes em relação aos tratamentos medicamentosos, com efeitos tanto benéficos como prejudiciais à saúde (efeito nocebo). Objetivo: Analisar a interação entre os fatores que ensejam o surgimento do efeito placebo e suas consequências nos tratamentos medicamentosos. Metodologia: Foi realizada uma pesquisa bibliográfica através de consultas nas bases de dados Scielo, PubMed, Lilacs e Google Acadêmico, tendo como critério de inclusão publicações dos últimos cinco anos. Resultados: Alguns estudos pontuam que o efeito placebo possui diversos efeitos no organismo humano, tendo sido evidenciado em diversas condições clínicas como: dor, depressão e doença de Parkinson. Tal fenômeno está relacionado com as expectativas dos pacientes em relação aos fármacos a eles administrados, tendo como consequências: respostas hormonais, efeitos analgésicos, aumento nos níveis de glicose e elevações no fluxo sanguíneo cerebral, com implicações na saúde física e mental. Ademais, outros estudos constataram que comandos internos e sugestões da mente decorrentes do estado emocional, humor, cognição e personalidade podem desencadear no organismo as respostas placebo e nocebo. Conclusões: Desta forma é importante, durante o tratamento medicamentoso, o acompanhamento dos valores, crenças, mitos e cultura dos pacientes que podem influenciar no surgimento de tais efeitos. Devido às suas diversas variáveis, que incluem fatores cognitivos, emocionais, sociais e fisiológicos, não existe um consenso metodológico que possibilite a elaboração de conclusões confiáveis e sólidas em relação aos fatores do efeito placebo. Contudo, devido aos efeitos consideráveis nos pacientes, tanto positivos como negativos, e sua grande aplicabilidade prática, são necessários estudos mais aprofundados em torno da neurobiologia de suas interações.

Publicado

2021-07-28

Como Citar

Silva Júnior, E. L. da ., & Gonzalez, L. F. C. . (2021). O EFEITO PLACEBO E SUAS IMPLICAÇÕES NOS TRATAMENTOS MEDICAMENTOSOS. Revista Multidisciplinar Em Saúde, 2(3), 18. https://doi.org/10.51161/rems/1418

Baixar Citação

Edição

v. 2 n. 3 (2021)

Seção

II Congresso Brasileiro de Saúde On-line

Licença

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

O conteúdo desta revista foi migrado para https://editoraintegrar.com.br

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
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                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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