DOENÇA HEPÁTICA ALCOÓLICA

Autores

  • Iara Desiree Vizotto
  • Juliana da Cruz Nunes Silva
  • Maryellen Orbolato Patussi
  • Luiza Mahiara Calixto Zussa
  • Paulo Giovani Padilha dos Santos

DOI:

https://doi.org/10.51161/rems/2820

Palavras-chave:

CIRROSE HEPÁTICA ALCOÓLICA, HEPATITE ALCOÓLICA

Resumo

Introdução: A doença hepática alcoólica (ALD), reporta-se aos danos que acometem o fígado e suas funções, devido ao excesso do consumo de álcool, resultando em várias patologias: esteatose, hepatite alcoólica, esteatohepatite, hepatite crônica com fibrose,  cirrose e câncer de fígado. A patogênese por trás da doença hepática alcoólica (ALD) possui mecanismos complexos devido ao comprometimento imunológico, sendo considerada a segunda causa mais comum de morte humana. Consumir bebida alcoólica a longo prazo em excesso, pode causar uma inflamação por meio de acúmulo de algumas substâncias que causam toxicidade no fígado, através do metabolismo do álcool. Objetivo: O trabalho tem como objetivo compilar da literatura o conhecimento sobre doença hepática alcoólica. Material e métodos: O estudo realizado foi uma revisão da literatura. Os dados extraídos na pesquisa foram a partir do PubMed com os descritores: “Liver Cirrhosis, Alcoholic” e “Hepatitis, Alcoholic” de acordo com os Descritores em Ciências da Saúde (DeCS). Para efetuar o cruzamento destes foi utilizado o operador booleano AND, encontrados 849 artigos e após critérios de inclusão e exclusão, 8 artigos foram utilizados. Os utilizados para a inclusão: artigos em inglês, português ou espanhol, entre junho de 2016 a julho de 2021, e disponíveis na íntegra e para acesso online grátis. Resultado: A ALD como abordado acima, tem um amplo espectro de distúrbios, sendo uma das principais causas de morbidade e mortalidade no mundo. Na Europa a cirrose hepática alcoólica foi responsável por 493.300 mortes em 2010. Nos EUA, a mortalidade por ALD foi estimada em 5,5 por 100.000 em 2012. No mundo as mortes por AC ocupam cerca de 10% de todas as mortes atribuídas ao álcool. Conclusão: Diante da alta taxa de mortalidade, tendo um conhecimento razoável, sabendo-se do quanto se é complexo e complicado o conhecimento da sua fisiopatologia, epidemiologia, patogenicidade, é notável a falha na detecção precoce para que seja feito um bom diagnóstico clínico. Fica evidente também, a deficiência, das terapêuticas utilizadas para tratamento, sendo necessária a utilização de novas terapias e de uma atenção maior a essa doença que acomete muitos pacientes, e que tem um nível razoavelmente baixo nas pesquisas.

Publicado

2021-12-17

Como Citar

Vizotto, I. D. . ., Silva, J. da C. N. ., Patussi, M. O. ., Zussa, L. M. C. ., & Santos, P. G. P. dos . (2021). DOENÇA HEPÁTICA ALCOÓLICA. Revista Multidisciplinar Em Saúde, 2(4), 64. https://doi.org/10.51161/rems/2820

Edição

v. 2 n. 4 (2021)

Seção

I Congresso Brasileiro de Saúde Pública On-line: Uma abordagem Multiprofissional

Licença

Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

O conteúdo desta revista foi migrado para https://editoraintegrar.com.br

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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