EXPOSIÇÃO A AGROTÓXICOS E AUMENTO DE OBESIDADE: UMA REVISÃO DA LITERATURA

Autores

  • Karen Cristine Silva de Oliveira
  • Calinca Skonieski
  • Heloisa Moreira Pestana De Medeiros
  • Larissa Da Silva
  • Dalila Moter Benvegnú

DOI:

https://doi.org/10.51161/rems/1504

Palavras-chave:

DEFENSIVOS AGRÍCOLAS, COMORBIDADE ASSOCIADAS, OBESIDADE

Resumo

Introdução: Nas últimas décadas a prevalência de obesidade tem aumentado globalmente. Vale ressaltar que a obesidade é uma doença multifatorial, e fatores como exposição a agrotóxicos têm sido relacionados com o ganho de peso. Objetivo: Diante disso, o objetivo deste estudo foi identificar a relação entre a exposição a agrotóxicos e desenvolvimento de obesidade. Material e métodos: Dessa maneira, foi realizada uma revisão sistemática da literatura. E para isso, foram utilizadas as bases de dados PUBMED, SCIENCE DIRECT e SCOPUS, e os descritores “obesidade e agrotóxicos” em inglês. A pesquisa resultou em 128 estudos e após a avaliação dos mesmos, excluiu-se trabalhos que não respeitavam os critérios de inclusão como: artigos originais com indivíduos adultos de ambos os sexos expostos a agrotóxicos e os quais deveriam apresentar a avaliação da obesidade como desfecho primário. Resultados: Dos estudos selecionados, cerca de 86% (13/15) apresentaram correlação positiva entre o ganho excessivo de peso corporal e a exposição a agrotóxicos. Ademais, foi possível observar que tal exposição também apresenta correlação positiva com o aumento dos níveis de glicose e de insulina (HbA1 e HOMA-IR). E possivelmente, a resistência insulínica, síndrome metabólica e hipertensão, bem como, pode relacionar-se com a desregulação da homeostase lipídica, ocasionando aumento dos níveis de triglicerídeos e diminuição do HDL. Além disso, os agrotóxicos que mais apresentaram correlação com o ganho de peso, foram os da classe organoclorados. Conclusão: Desse modo, os resultados demonstram que a exposição a agrotóxicos pode estar relacionada com o aumento dos casos de obesidade e comorbidades associadas como por exemplo doenças cardíacas, dislipidemias e diabetes. Entretanto, ainda são necessárias novas investigações acerca desta temática, para que seja possível a melhor compreensão dos mecanismos envolvidos. 

Publicado

2021-07-28

Como Citar

Oliveira, K. C. S. de ., Skonieski, C., Medeiros, H. M. P. D. ., Silva, L. D. ., & Benvegnú, D. M. . (2021). EXPOSIÇÃO A AGROTÓXICOS E AUMENTO DE OBESIDADE: UMA REVISÃO DA LITERATURA. Revista Multidisciplinar Em Saúde, 2(3), 92. https://doi.org/10.51161/rems/1504

Edição

Seção

II Congresso Brasileiro de Saúde On-line
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   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php
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                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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