EFEITO ANTIMICROBIANO DE COMPOSTOS TRIAZÓLICOS EM CEPAS DE Staphylococcus aureus ISOLADAS DE CASOS DE MASTITE EM BOVINOS.

Eduarda Socovoski  Gnoatto; Vitoria Karolini Betim Fieldkircher  Caus; Cristian Ferreira Corona; Letiére Cabreira  Soares; Dalila Moter  Benvegnú

doi:10.51161/rems/1198

EFEITO ANTIMICROBIANO DE COMPOSTOS TRIAZÓLICOS EM CEPAS DE Staphylococcus aureus ISOLADAS DE CASOS DE MASTITE EM BOVINOS.

Autores

Eduarda Socovoski Gnoatto
Vitoria Karolini Betim Fieldkircher Caus
Cristian Ferreira Corona
Letiére Cabreira Soares
Dalila Moter Benvegnú

DOI:

https://doi.org/10.51161/rems/1198

Palavras-chave:

ATIVIDADE ANTIMICROBIANA, GLÂNDULA MAMÁRIA, PECUÁRIA, RESISTÊNCIA MICROBIANA, TRIAZOL

Resumo

Introdução: A mastite bovina é a principal enfermidade da indústria leiteira mundial, a qual desencadeia um processo inflamatório na glândula mamária de bovinos. Esta doença é causada principalmente por bactérias, que predominam devido às más condições higiênico-sanitárias no ambiente e péssimas condições de saúde dos animais. O uso indiscriminado de antibióticos em rebanhos leiteiros tem gerado aumento da resistência bacteriana, dificultando o tratamento dessa doença, o que por sua vez acaba prejudicando o bem-estar do animal e a qualidade do leite produzido. E, dentre as diversas bactérias pode ser citado o Staphylococcus aureus, que se destaca devido á sua resistência. À vista disso, pesquisas têm buscado alternativas para tratamento desta doença, os quais não acarretem mais resistência bacteriana. Um exemplo disto é a utilização de compostos triazólicos e seus derivados, que se destacam na área de química medicinal e podem ser usados para a síntese de vários compostos heterocíclicos com diferentes atividades biológicas como: antiviral, antibacteriana, antifúngica e antituberculose. Objetivo: Realizar uma revisão da literatura sobre ação antimicrobiana de compostos triazólicos sobre S. aureus. Métodos: Foi realizada uma revisão bibliográfica no banco de dados Scholar Google no qual foram selecionados trabalhos entre os anos de 2008 e 2020 com um nº de 16, cujos termos utilizados foram: "triazol", "antimicrobial" e "S. aureus". Resultado: Os métodos mais utilizados para avaliação da atividade antimicrobiana foram Difusão em poço e Concentração Inibitória Mínima. Os compostos derivados de triazol, em todos os estudos apresentaram efeito antimicrobiano significativo em relação às cepas de S. aureus. Alguns trabalhos relataram que geralmente a presença de qualquer substituinte no anel benzeno presente no composto levou ao aumento da atividade antimicrobiana frente a todas as cepas bacterianas testadas. Além disso, foi demonstrado que a presença de átomos ou grupos que retiram ou doam elétrons nas posições orto ou para em relação à fenila ligada ao triazol é capaz de aumentar a atividade antibacteriana desses compostos. Conclusão: Por meio da revisão bibliográfica deste estudo, observou-se que os compostos derivados de triazol têm sido relatados por apresentarem notável efeito antimicrobiano em cepas de S. aureus.

Publicado

2021-06-12

Como Citar

Gnoatto, E. S. ., Caus, V. K. B. F. ., Corona, C. F., Soares, L. C., & Benvegnú, D. M. . (2021). EFEITO ANTIMICROBIANO DE COMPOSTOS TRIAZÓLICOS EM CEPAS DE Staphylococcus aureus ISOLADAS DE CASOS DE MASTITE EM BOVINOS. Revista Multidisciplinar Em Saúde, 2(2), 41. https://doi.org/10.51161/rems/1198

Baixar Citação

Edição

v. 2 n. 2 (2021): Edição Especial: Anais de Eventos

Seção

Anais do I Congresso Nacional de Microbiologia Clínica On-Line

Licença

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

O conteúdo desta revista foi migrado para https://editoraintegrar.com.br

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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