Toxoplasma gondii NA GESTAÇÃO - DANOS NO DESENVOLVIMENTO FETAL

Autores

  • Gabriela Koh Hammacher
  • Saulo Bueno de Azeredo
  • Natália Gonçalves Rengel
  • Gean Scherer da Silva
  • Fabiana Tonial

DOI:

https://doi.org/10.51161/rems/704

Palavras-chave:

Dano fetal, Infecção congênita, Protozoário, Toxoplasmose

Resumo

Introdução: A toxoplasmose é uma parasitose provocada pelo Toxoplasma gondii, essa doença acomete aproximadamente um terço da população mundial. Apesar de sua alta incidência, o microrganismo possui baixa patogenicidade. No entanto, quando a primoinfecção ocorre na gestação ela pode resultar em graves consequências para o desenvolvimento do feto. Assim, é de suma importância o rastreio de toxoplasmose na gestação com intuito de diagnóstico e tratamento precoce, reduzindo os possíveis danos materno-fetais. Objetivo: Descrever as principais consequências fetais promovidas por infecção materna na gestação pelo Toxoplasma gondii evidenciadas na literatura. Material e métodos: Foi realizada uma revisão narrativa da literatura utilizando as bases de dados “PubMed” e “SciELO”, sendo usados para a busca a combinação dos seguintes descritores em inglês: “Toxoplasma gondii", "toxoplasmose", "gestação", "congênita”. Resultados: As consequências da toxoplasmose congênita dependem do grau de exposição do feto aos protozoários, da virulência da cepa infectante e do período gestacional. No primeiro trimestre de gestação a chance de contaminação materno-fetal fica em torno de 15%, pode ocorrer morte fetal e graves danos neurológicos. No terceiro trimestre de gestação a transmissão materno-fetal aumenta significativamente, é, em média, de 60%, e os danos fetais mais comuns são: retinocorodite, calcificação cerebral, hidrocefalia e retardo mental. As formas graves desse acometimento são divididas em generalizadas e neurológicas. Na forma generalizada pode ocorrer alterações liquóricas, linfadenopatia, trombocitopenia, hepatoesplenomegalia e icterícia. Em casos de doença neurológica pode ocorrer calcificações intracranianas, coriorretinite, hidrocefalia, convulsão e microcefalia. Conclusão: A primo-infecção por toxoplasmose no primeiro e no terceiro trimestres de gestação pode desencadear acometimentos graves ao feto, os quais justificam a necessidade de um consenso em relação ao rastreio, diagnóstico e tratamento da doença na gestação.

Publicado

2021-03-01

Como Citar

Hammacher, G. K., de Azeredo, S. B., Rengel, N. G., Silva, G. S. da, & Tonial, F. (2021). Toxoplasma gondii NA GESTAÇÃO - DANOS NO DESENVOLVIMENTO FETAL. Revista Multidisciplinar Em Saúde, 2(1), 26. https://doi.org/10.51161/rems/704

Edição

Seção

Anais do Congresso Brasileiro de Parasitologia Humana On-line

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php
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                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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