OS EFEITOS DO GLUTAMATO MONOSSÓDICO NO SISTEMA NERVOSO CENTRAL E NO METABOLISMO: UMA REVISÃO SISTEMÁTICA

Autores

  • Mariana Schmidt Cheaitou
  • Maria Clara Lopes Rezende
  • Diúle Nunes Sales
  • Vitor De Paula Boechat Soares
  • Sofia D'anjos Rodrigues

DOI:

https://doi.org/10.51161/rems/1497

Palavras-chave:

GLUTAMATO MONOSSÓDICO, METABOLISMO, SISTEMA NERVOSO CENTRAL

Resumo

Introdução: O glutamato monossódico (MSG) é um aditivo colocado durante o preparo dos alimentos para potencializar o sabor. Entretanto, o seu consumo em excesso (>2%) pode ocasionar tonturas, cefaléia e dores nos membros 20 minutos após a ingestão. Além disso, os efeitos adversos são mais perceptíveis no sexo feminino em relação ao masculino e se o MSG for consumido após o jejum e dissociado de alimentos. Objetivo: Investigar os efeitos da ingesta de MSG no organismo humano. Materiais e Métodos: Foi realizada uma revisão sistemática de literatura, analisando estudos publicados na base de dados PubMed. A frase de pesquisa foi construída mediante consulta ao MeSH com os descritores: Glutamato monossódico, Enxaqueca e Cefaleia. Resultados: O MSG é capaz de alterar o sabor dos alimentos, já que tende a ser menos palatável. Em relação à dor, é dito que o MSG torna os músculos da mastigação e outros músculos esqueléticos mais sensibilizados e está mais concentrado em regiões dolorosas no músculo, causando diversos tipos de dores, como a craniofacial, além das cefaleias. O MSG desencadeia a liberação de óxido nítrico, que provoca a dilatação de vasos sanguíneos intracranianos e extracranianos, desencadeando a cefaleia. Sabe-se que o MSG está relacionado com toxicidades, como disfunções metabólicas, efeitos neurotóxicos, comprometimento dos órgãos reprodutivos, danos hepáticos, perturbação na fisiologia do tecido adiposo e obesidade. Ademais, o glutamato pode ser encontrado na sua forma natural em alimentos como peixes, tomates, queijos. Tanto glutamato natural, quanto MSG são metabolizados da mesma forma, uma vez que o glutamato é uma proteína importante. O consumo de MSG é vantajoso por reduzir a ingesta de cloreto de sódio, o que ajuda pacientes que necessitam de dietas hipossódica. Porém tal substituição não é totalmente vantajosa, já que o MSG pode causar elevação da pressão arterial e da frequência cardíaca. Conclusão: O MSG potente aditivo na culinária, é encontrado em fast food e em temperos prontos. Ele é um estimulador para desencadear ou agravar dores de cabeça, que possuem efeitos mais frequentes nas mulheres, bem como para causar alterações na pressão arterial. Os sintomas são cefaleias, dormências, distúrbios gastrointestinais, tonturas, vómitos

Publicado

2021-07-28

Como Citar

Cheaitou , M. S. ., Rezende, M. C. L. ., Sales, D. N., Soares, V. D. P. B. ., & Rodrigues, S. D. . (2021). OS EFEITOS DO GLUTAMATO MONOSSÓDICO NO SISTEMA NERVOSO CENTRAL E NO METABOLISMO: UMA REVISÃO SISTEMÁTICA. Revista Multidisciplinar Em Saúde, 2(3), 86. https://doi.org/10.51161/rems/1497

Edição

Seção

II Congresso Brasileiro de Saúde On-line
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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php
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                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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