DOSAGEM DE IMUNOGLOBULINA A E PROTEÍNAS TOTAIS EM AMOSTRAS DO BANCO DE LEITE HUMANO DE BLUMENAU/SC

Autores

  • Keila Zaniboni Siqueira Batista
  • Andressa Karine Boehringer
  • Marina Schndeider
  • Vinicius Vialle Ferreira
  • Mercedes Gabriela Ratto Reiter

DOI:

https://doi.org/10.51161/rems/959

Palavras-chave:

Anticorpos, Diagnósticos Laboratoriais, Imunidade Passiva, Leite Humano, Saúde Materno-infantil

Resumo

Introdução: O leite humano apresenta componentes indispensáveis para defesa e proteção do recém-nascido. Variações na qualidade do leite materno afetam o desenvolvimento, saúde e crescimento do recém-nascido, tornando-o vulnerável. Objetivos: determinar a dosagem de Imunoglobulina A (IgA) e proteínas totais em amostras de leite materno do Banco de Leite Humano (BLH) de Blumenau/SC; assim como determinar possíveis fatores que podem influenciar nessas dosagens. Material e métodos: Estudo transversal, com análise de 105 amostras de leite provenientes do BLH de Blumenau/SC. A dosagem das proteínas totais foi realizada em equipamento Human Milk Analyser (HMA) por metodologia de infravermelho, enquanto a dosagem da IgA foi realizada pela técnica de turbidimetria. Dados sobre estágio do leite, idade materna, IMC, tipo de parto, tempo gestacional e peso do bebê ao nascer também foram coletados. Resultados: Em relação a dosagem do anticorpo secretório, o leite maduro apresentou uma redução de 26% na quantidade de IgA em relação ao colostro. Quando associado ao tipo de parto, observou-se uma redução de 21% na quantidade de proteínas do leite materno quando realizado parto vaginal. Os valores de proteínas totais apresentaram correlação estatisticamente significativa com a idade gestacional, IMC inicial e final. A correlação do nível de proteínas totais com o IMC, tanto inicial como final da mãe, demonstrou que há influência sobre a dosagem de proteínas no leite materno, ou seja, quanto maior o IMC da mãe, maior a dosagem de proteínas totais do leite. Não houve diferenças significativas entre IgA com as demais variáveis analisadas. Apesar disso, a quantidade de IgA apresentou uma tendência decrescente em relação ao aumento da idade materna. Conclusão: a dosagem média das proteínas foi relativamente abaixo da média da literatura; diferindo da dosagem da IgA que se apresentou como esperado. Houve redução na dosagem de IgA no leite maduro em relação ao colostro e diminuição na quantidade de proteínas no parto vaginal. Quanto as correlações, a variável proteínas apresentou associação com Idade materna, IMC inicial e final; diferente da variável IgA, na qual não houve nenhuma correlação significativa.

Publicado

2021-04-24

Como Citar

Batista, K. Z. S., Boehringer, A. K., Schndeider, M., Ferreira, V. V., & Reiter, M. G. R. (2021). DOSAGEM DE IMUNOGLOBULINA A E PROTEÍNAS TOTAIS EM AMOSTRAS DO BANCO DE LEITE HUMANO DE BLUMENAU/SC. Revista Multidisciplinar Em Saúde, 2(2), 17. https://doi.org/10.51161/rems/959

Edição

Seção

Anais do Congresso Brasileiro de Imunologia On-line

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PKPApplication.execute() % line   68, file: index.php
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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php
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                                                         SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[1], , null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php