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v. 2 n. 1 (2021): Edição Especial: Anais de Eventos
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Anais do Congresso Brasileiro de Hematologia Clínico-laboratorial On-line
VALOR PLAQUETÁRIO MÍNIMO PARA A TERAPIA TRANSFUSACIONAL EM PACIENTES COM DENGUE
Autores
Gabrielle Dos Santos Moreira
Daniele Das Dores Mota Oliveira
Roberto Pacheco De Almeida Segundo
Amandha Victória De Pinho Gonzaga Rodrigues
Maria Eduarda Da Silva Cursino Ribeiro
Palavras-chave:
Dengue, Hematologia, Terapia transfusional
Resumo
Introdução: Considerada um problema de saúde pública em todo o mundo, a dengue possui 4 sorotipos transmitidos pelo mosquito Aedes aegypti. Seus achados mais comuns são a febre, dor de cabeça, mal-estar geral, erupção cutânea, prurido, diarreia, náusea, dificuldade respiratória e sangramento. Alguns aspectos laboratoriais são um aumento no hematócrito, leucopenia, linfocitose relativa e baixa contagem de plaquetas. Por essa razão, surgi a necessidade de um conhecimento científico que correlacione a terapia transfusional com o valor mínimo de plaquetas que beneficiariam o paciente. Objetivo: Analisar o valor mínimo de plaquetas para o início da transfusão plaquetária em pacientes com dengue na literatura médica nos últimos 15 anos. Material e métodos: Trata-se de uma revisão na literatura a qual utilizou-se as bases de dados Pubmed e Sciello, entre os anos de 2005 a 2020. Foram incluídos artigos direcionados a terapia transfusional em pacientes com dengue e excluídos textos incompletos, capítulos de livros, teses de doutorado e dissertações de mestrado. Utilizaram-se os descritores em português, espanhol e inglês. Resultados: Os artigos encontrados trazem que tais achados clínicos são decorrentes da destruição plaquetária periférica, que ocorre no baço e no fígado, em razão da ação dos imunocomplexos ou do sistema complemento. O Ministério da Saúde recomenda que a terapia ocorra quando os níveis plaquetários forem inferiores a 20 × 10 9 / L com sangramento significativo ou quando a contagem de plaquetas variar de 20- 50 × 10 9 / L com suspeita de sangramento do sistema nervoso central (SNC), entretanto outros autores variam esse valor. Conclusão: De acordo com os inúmeros achados clínicos da patologia, percebe-se a necessidade de que ensaios clínicos sejam realizados para estabelecimento de tal valor limite.
Como Citar
Moreira, G. D. S., Oliveira, D. D. D. M., Segundo, R. P. D. A., Rodrigues, A. V. D. P. G., & Ribeiro, M. E. D. S. C. (2021). VALOR PLAQUETÁRIO MÍNIMO PARA A TERAPIA TRANSFUSACIONAL EM PACIENTES COM DENGUE . Revista Multidisciplinar Em Saúde , 2 (1), 38. https://doi.org/10.51161/rems/786
Seção
Anais do Congresso Brasileiro de Hematologia Clínico-laboratorial On-line
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