VALOR PLAQUETÁRIO MÍNIMO PARA A TERAPIA TRANSFUSACIONAL EM PACIENTES COM DENGUE

Autores

  • Gabrielle Dos Santos Moreira
  • Daniele Das Dores Mota Oliveira
  • Roberto Pacheco De Almeida Segundo
  • Amandha Victória De Pinho Gonzaga Rodrigues
  • Maria Eduarda Da Silva Cursino Ribeiro

DOI:

https://doi.org/10.51161/rems/786

Palavras-chave:

Dengue, Hematologia, Terapia transfusional

Resumo

Introdução: Considerada um problema de saúde pública em todo o mundo, a dengue possui 4 sorotipos transmitidos pelo mosquito Aedes aegypti. Seus achados mais comuns são a febre, dor de cabeça, mal-estar geral, erupção cutânea, prurido, diarreia, náusea, dificuldade respiratória e sangramento. Alguns aspectos laboratoriais são um aumento no hematócrito, leucopenia, linfocitose relativa e baixa contagem de plaquetas. Por essa razão, surgi a necessidade de um conhecimento científico que correlacione a terapia transfusional com o valor mínimo de plaquetas que beneficiariam o paciente. Objetivo: Analisar o valor mínimo de plaquetas para o início da transfusão plaquetária em pacientes com dengue na literatura médica nos últimos 15 anos. Material e métodos: Trata-se de uma revisão na literatura a qual utilizou-se as bases de dados Pubmed e Sciello, entre os anos de 2005 a 2020. Foram incluídos artigos direcionados a terapia transfusional em pacientes com dengue e excluídos textos incompletos, capítulos de livros, teses de doutorado e dissertações de mestrado. Utilizaram-se os descritores em português, espanhol e inglês. Resultados: Os artigos encontrados trazem que tais achados clínicos são decorrentes da destruição plaquetária periférica, que ocorre no baço e no fígado, em razão da ação dos imunocomplexos ou do sistema complemento. O Ministério da Saúde recomenda que a terapia ocorra quando os níveis plaquetários forem inferiores a 20 × 10 9 / L com sangramento significativo ou quando a contagem de plaquetas variar de 20- 50 × 10 9 / L com suspeita de sangramento do sistema nervoso central (SNC), entretanto outros autores variam esse valor. Conclusão: De acordo com os inúmeros achados clínicos da patologia, percebe-se a necessidade de que ensaios clínicos sejam realizados para estabelecimento de tal valor limite.

Publicado

2021-02-01

Como Citar

Moreira, G. D. S., Oliveira, D. D. D. M., Segundo, R. P. D. A., Rodrigues, A. V. D. P. G., & Ribeiro, M. E. D. S. C. (2021). VALOR PLAQUETÁRIO MÍNIMO PARA A TERAPIA TRANSFUSACIONAL EM PACIENTES COM DENGUE . Revista Multidisciplinar Em Saúde, 2(1), 38. https://doi.org/10.51161/rems/786

Edição

Seção

Anais do Congresso Brasileiro de Hematologia Clínico-laboratorial On-line
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