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v. 2 n. 1 (2021): Edição Especial: Anais de Eventos
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Anais do Congresso Brasileiro de Hematologia Clínico-laboratorial On-line
DISFUNÇÕES HEMATOLÓGICAS EM PACIENTES COM LÚPUS ERITEMATOSO SISTÊMICO: REVISÃO INTEGRATIVA
Autores
Maria Vitória Ribeiro de Moraes Macedo
Ana Paula de Castro Pires
João Paulo de Castro Marcondes
Palavras-chave:
Lúpus Eritematoso Sistêmico, Alterações Hematológicas, Paciente
Resumo
Introdução: O Lúpus Eritematoso Sistêmico (LES) é uma doença autoimune de etiologia multifatorial cuja patogênese está relacionada à formação de complexos imunes que induzem o processo inflamatório e levam à lesão tecidual. Os sinas e sintomas mais comuns são fadiga, perda de apetite, febre, artrite e podem variar de acordo com a gravidade da doença e o órgão afetado. As alterações hematológicas (AH) são frequentes e preocupantes no quadro clínico do paciente, podendo estar associadas às lesões teciduais promovidas pela doença. Objetivo: Dada a escassez de estudos longitudinais associando as principais AH com as manifestações clínicas do LES, objetivou-se com o presente estudo conduzir uma revisão integrativa da literatura na tentativa de elucidar a significância das principais AH no desenvolvimento e progressão do LES. Material e Métodos: Realizou-se uma revisão integrativa (2010 a 2020) sobre as AH em pacientes com LES utilizando-se as bases de dados científicos (MEDLINE, PUBMED, e Google Scholar).Resultados: Através do critério de classificação da doença LES analisou-se os valores de referência dos componentes sanguíneos e os fatores agravantes das manifestações hematológicas mais comuns no quadro clinico, como a Leucopenia, Linfopenia, Trombocitopenia e Anemia hemolítica todas caracterizadas por contagens celulares abaixo do normal, contribuindo para a prevalência dos sintomas no paciente. Conclusão: Por meio de exames hematológicos foi possível identificar alterações associadas ao Lúpus. Por ser uma doença de difícil diagnose, novos estudos e pesquisas acerca das alterações hematológicas podem permitir mais acessos e desenvolvimento ao diagnóstico e tratamento para o paciente com LES.
Como Citar
Macedo, M. V. R. de M., Pires, A. P. de C., & Marcondes, . J. P. de C. (2021). DISFUNÇÕES HEMATOLÓGICAS EM PACIENTES COM LÚPUS ERITEMATOSO SISTÊMICO: REVISÃO INTEGRATIVA. Revista Multidisciplinar Em Saúde , 2 (1), 15. https://doi.org/10.51161/rems/640
Seção
Anais do Congresso Brasileiro de Hematologia Clínico-laboratorial On-line
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