FOTOTERAPIA COM UVBNB E PUVA NO TRATAMENTO DA PSORÍASE MODERADA A GRAVE

Luiza Helena Angarten Ferraz de Camargo; Sarah Amancio Valvassoura; Maísa Ribeiro

FOTOTERAPIA COM UVBNB E PUVA NO TRATAMENTO DA PSORÍASE MODERADA A GRAVE

Autores

Luiza Helena Angarten Ferraz de Camargo
Sarah Amancio Valvassoura
Maísa Ribeiro

Palavras-chave:

associação terapêutica, benefícios, fototerapia, psoríase

Resumo

Introdução: A psoríase é uma doença dermatológica de caráter crônico que afeta cerca de 1 a 3% da população mundial e se caracteriza pela hiperplasia epidérmica associada à inflamação com presença de placas eritemato-descamativas. A fototerapia tem demonstrado alta eficiência terapêutica no tratamento de psoríase, e tem sido utilizada associada a fármacos biológicos desde o início da década de 80. Objetivo: O presente trabalho tem como objetivo realizar uma revisão de literatura integrativa no período de 2015 à 2020, a fim de atestar que a associação fototerapia-terapêutica biológica possui efeitos benéficos no tratamento da psoríase. Material e métodos: Trata-se de um estudo de revisão literária com análises de artigos consultados nas bases de dados Google Acadêmico, Scielo e Portal de Periódicos, utilizando os descritores psoríase e fototerapia. Resultados: Após aplicar os critérios de inclusão e exclusão, 03 (três) artigos foram selecionados para síntese. Os resultados permitiram evidenciar que em casos de manifestações moderadas ou graves da psoríase, a terapia tópica não é suficiente, sendo a fototerapia o método mais indicado. A luz UV tem propriedades imunossupressoras, anti-inflamatórias e antiproliferativas. A radiação UV é dividida em UVA e UVB, que por sua vez é chamada UVB banda estreita ou UVBnb (UVB “narrow band”) na faixa entre 311 e 312nm, que é a faixa da radiação UVB utilizada no tratamento de pacientes com psoríase. Também vem sendo comprovada a efetividade do tratamento da doença por meio da fototerapia com PUVA, realizada pela associação de um psoralênico e irradiação de UVA de comprimentos de onda entre 320 e 400nm. Estudos clínicos têm demonstrado eficácia na redução no aparecimento de placas eritemato-descamativas por meio da junção terapêutica biológica com estes formatos de fototerapia. Prescrições de UVBnb e PUVA permitem aumento da resposta terapêutica sem necessidade do aumento de doses dos fármacos biológicos. Apesar destes aspectos positivos, a segurança do tratamento ao longo dos anos ainda é desconhecida. Conclusão: A associação da fototerapia ao tratamento medicamentoso se mostrou uma opção eficaz e de baixo custo na psoríase refratária ou agudizada. Porém, ainda são necessários estudos mais alargados para determinar a sua segurança a longo prazo.

Publicado

2020-09-01

Como Citar

Camargo, L. H. A. F. de, Valvassoura, S. A., & Ribeiro, M. (2020). FOTOTERAPIA COM UVBNB E PUVA NO TRATAMENTO DA PSORÍASE MODERADA A GRAVE. Revista Multidisciplinar Em Saúde, 1(3), 16. Recuperado de https://editoraime.com.br/revistas/rems/article/view/360

Baixar Citação

Edição

v. 1 n. 3 (2020): Edição Especial: Anais do I Congresso Brasileiro de Saúde On-line

Seção

Anais de Evento

Licença

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

O conteúdo desta revista foi migrado para https://editoraintegrar.com.br

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php