Início
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Arquivos
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v. 2 n. 4 (2021)
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I Congresso On-line Nacional de Histologia e Embriologia Humana
ASSOCIAÇÃO DA GASTRITE CRÔNICA COM HELICOBACTER PYLORI
Autores
Mahala Salem
Richam Gaze Hajar
Palavras-chave:
GASTRITE, GASTROENTEROPATIAS, HELICOBACTER PYLORI
Resumo
Introdução: A gastrite crônica é principalmente causada pelo hipercloridrismo no piloro por infecção pelo Helicobacter pylori. Essa bactéria é um bacilo flagelado espiralado que se localiza sobre o epitélio da área antro-piloro. Nessa região, altera a fisiologia local e inibe o feedback negativo, inativando as células D e induzindo a hipercloridria. A virulência do H. pilory é baseada em 4 fundamentos: Flagelos: mobilidade no muco; Urease: eleva o pH gástrico; Adesinas: aderência às células foveolares (glândulas gástricas) – presente na biópsia e fator determinante para o diagnóstico e Toxinas: CagA (úlcera e câncer associado – metaplasia intestinal). Objetivos: O presente estudo visa verificar os fatores associados com o diagnóstico de gastrite crônica e a presença do H. pylori e demonstrar a importância da prevenção e tratamento da doença. Material e métodos: Este trabalho trata-se de uma revisão bibliográfica, que visa demonstração de características sobre manifestação clínica da gastrite associada ao H. pylori baseada em estudos passados. Para a realização do estudo, foram utilizados livros e artigos encontrados em sites acadêmicos como Google acadêmico e Scielo. Resultado: O Helicobacter pylori causa gastrite ao estimular a produção de citocinas pró-inflamatórias e destruir diretamente as células epiteliais. A gastrite é dividida em duas categorias, aguda e crônica, ambas com diferentes graus de descamação da superfície epitelial gástrica e diferentes graus de infiltração inflamatória. Na fase aguda, pode haver casos leves sem grandes alterações inflamatórias, enquanto em casos mais graves a inflamação pode ter sangramento adicional ou mesmo erosões da mucosa. A inflamação crônica da mucosa causada pelo Helicobacter pylori reduz a secreção ácida, levando à hipoacidez, além de reduzir a secreção de pepsina, contribuindo na proliferação bacteriana e na persistência da doença, aumentando o risco de mutações genômicas. Conclusão: A gastrite é uma patologia caracterizada por alterações histológicas na mucosa gástrica, na qual se observa infiltração de células inflamatórias. É a lesão mais comum que acomete o estômago. Pode-se concluir que múltiplas etiologias interagem para o aparecimento da gastrite crônica. Em palavras derradeiras, deve-se manter uma nutrição adequada ao longo da vida como método profilático contra o aparecimento de gastrite e o Helicobacter pylori.
Como Citar
Salem, M. ., & Hajar, R. G. . (2022). ASSOCIAÇÃO DA GASTRITE CRÔNICA COM HELICOBACTER PYLORI. Revista Multidisciplinar Em Saúde , 2 (4), 23. https://doi.org/10.51161/rems/3206
Seção
I Congresso On-line Nacional de Histologia e Embriologia Humana
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PKPPageRouter.route(Object:Request) % line 143, file: Dispatcher.inc.php
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DAO.retrieveCached(SELECT o.submission_id, MAX(s.context_id) AS journal_id, MAX(i.date_published) AS i_pub, MAX(p.date_published) A..., Array[2], 3600) % line 91, file: ArticleSearchDAO.inc.php
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PKPApplication.execute() % line 68, file: index.php
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SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line 194, file: SubmissionSearch.inc.php
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SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line 132, file: SubmissionSearch.inc.php
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SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line 92, file: RecommendBySimilarityPlugin.inc.php
RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line 107, file: HookRegistry.inc.php
HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
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DAO.retrieveCached(SELECT o.submission_id, MAX(s.context_id) AS journal_id, MAX(i.date_published) AS i_pub, MAX(p.date_published) A..., Array[2], 3600) % line 91, file: ArticleSearchDAO.inc.php
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SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line 92, file: RecommendBySimilarityPlugin.inc.php
RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line 107, file: HookRegistry.inc.php
HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line 43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
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Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line 924, file: PKPTemplateManager.inc.php
PKPTemplateManager.display(frontend/pages/article.tpl) % line 292, file: ArticleHandler.inc.php
ArticleHandler.view(Array[1], Object:Request) % line 391, file: PKPRouter.inc.php
PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line 231, file: PKPPageRouter.inc.php
PKPPageRouter.route(Object:Request) % line 143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line 281, file: PKPApplication.inc.php
PKPApplication.execute() % line 68, file: index.php
ADOConnection.CacheExecute(3600, SELECT o.submission_id, MAX(s.context_id) AS journal_id, MAX(i.date_published) AS i_pub, MAX(p.date_published) A..., Array[2]) % line 132, file: DAO.inc.php
DAO.retrieveCached(SELECT o.submission_id, MAX(s.context_id) AS journal_id, MAX(i.date_published) AS i_pub, MAX(p.date_published) A..., Array[2], 3600) % line 91, file: ArticleSearchDAO.inc.php
ArticleSearchDAO.getPhraseResults(Object:Journal, Array[1], null, null, , 500, 1) % line 201, file: SubmissionSearch.inc.php
SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[1], , null, null, 500, 1) % line 146, file: SubmissionSearch.inc.php
SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line 194, file: SubmissionSearch.inc.php
SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line 146, file: SubmissionSearch.inc.php
SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line 132, file: SubmissionSearch.inc.php
SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line 263, file: SubmissionSearch.inc.php
SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line 92, file: RecommendBySimilarityPlugin.inc.php
RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line 107, file: HookRegistry.inc.php
HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line 43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
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Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line 114, file: smarty_template_compiled.php
Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line 216, file: smarty_internal_template.php
Smarty_Internal_Template.render(false, 1) % line 232, file: smarty_internal_templatebase.php
Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line 134, file: smarty_internal_templatebase.php
Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line 924, file: PKPTemplateManager.inc.php
PKPTemplateManager.display(frontend/pages/article.tpl) % line 292, file: ArticleHandler.inc.php
ArticleHandler.view(Array[1], Object:Request) % line 391, file: PKPRouter.inc.php
PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line 231, file: PKPPageRouter.inc.php
PKPPageRouter.route(Object:Request) % line 143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line 281, file: PKPApplication.inc.php
PKPApplication.execute() % line 68, file: index.php
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