Início
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Arquivos
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v. 2 n. 4 (2021)
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I Congresso On-line Nacional de Histologia e Embriologia Humana
OSTEOPOROSE: FISIOPATOLOGIA DAS ALTERAÇÕES HISTOLÓGICAS DO TECIDO ÓSSEO E PREVENÇÃO COM ATIVIDADE FÍSICA
Autores
Letícia Furtado Alves
Izadora Lima da Cruz
João Vittor Fonseca Pio
Karine Panuce de Oliveira
Karina Magalhães da Mata
Palavras-chave:
HISTOLOGIA, OSTEOPOROSE, ATIVIDADE FÍSICA
Resumo
Introdução: A diminuição da taxa de mortalidade está diretamente associada a um aumento da expectativa de vida, resultando no envelhecimento da população. Em uma população senil o aparecimento de doenças crônico-degenerativas é comum, sendo a osteoporose a que mais se destaca. Esta, é um distúrbio osteometabólico, onde ocorre perda de massa óssea e desarranjo da microarquitetura histológica do tecido ósseo. Assim, dá-se a relevância da prevenção com atividade física. Objetivos: elucidar as alterações histológicas da osteoporose e a prevenção com atividade física. Material e Métodos: Trata-se de uma revisão literária fundamentada nas bases de dados SciELO (Scientific Eletronic Library Online), PubMED e Web science baseados em artigos sobre alterações histológicas da osteoporose e a prevenção com atividade física realizados entre os períodos de 2006 a 2016, sendo no final selecionados 18 artigos. Resultados: Após analisar os resultados das pesquisas que compõem este estudo, foram observadas alterações histológica como o aumento da porosidade óssea, rarefação, alterações na microarquitetura dos ossos esponjosos e corticais, diminuição das fibras colágenas, evidências de desmineralização da matriz óssea, aumento do número de osteoclastos, diminuição de osteócitos e de osteoblastos. A constituição normal do osso, que seria uma parte inorgânica, composta por íons de fosfato e cálcio e outra orgânica, formada principalmente por fibras colágenas, apresentou-se alterada. Sabe-se que a fisiopatologia das alterações histológicas do tecido ósseo se baseia no desequilíbrio do metabolismo ósseo, gerando um aumento da reabsorção e diminuição da formação óssea. serão Os principais fatores desencadeadores dos mecanismos fisiopatológicos são as alterações hormonais, idade avançada, deficiência de vitamina D, carência de cálcio e sedentarismo. A osteoporose gera fraturas, deformações, diminuição da estatura, dor, invalidez e óbito. A atividade física regular previne a osteoporose e suas consequências por atuar no osso por efeito direto, via força mecânica, ou indireto, por fatores hormonais. Conclusão: Após realização desta revisão de literatura, nossos achados sugerem que a atividade física está associada à diversos benefícios sobre o tecido ósseo, tanto em pessoas saudáveis como em pessoas predispostas a osteoporose, com isso, terapêuticas mais adequadas podem ser desenvolvidas.
Como Citar
Alves, L. F. ., Cruz, I. L. da ., Pio, J. V. F. ., Oliveira, K. P. de ., & Karina Magalhães da Mata. (2021). OSTEOPOROSE: FISIOPATOLOGIA DAS ALTERAÇÕES HISTOLÓGICAS DO TECIDO ÓSSEO E PREVENÇÃO COM ATIVIDADE FÍSICA. Revista Multidisciplinar Em Saúde , 2 (4), 9. https://doi.org/10.51161/rems/2717
Seção
I Congresso On-line Nacional de Histologia e Embriologia Humana
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DAO.retrieveCached(SELECT o.submission_id, MAX(s.context_id) AS journal_id, MAX(i.date_published) AS i_pub, MAX(p.date_published) A..., Array[2], 3600) % line 91, file: ArticleSearchDAO.inc.php
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SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line 132, file: SubmissionSearch.inc.php
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SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line 132, file: SubmissionSearch.inc.php
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HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
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Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line 924, file: PKPTemplateManager.inc.php
PKPTemplateManager.display(frontend/pages/article.tpl) % line 292, file: ArticleHandler.inc.php
ArticleHandler.view(Array[1], Object:Request) % line 391, file: PKPRouter.inc.php
PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line 231, file: PKPPageRouter.inc.php
PKPPageRouter.route(Object:Request) % line 143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line 281, file: PKPApplication.inc.php
PKPApplication.execute() % line 68, file: index.php
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