CONSEQUÊNCIAS DA INGESTÃO DEFICITÁRIA DA VITAMINA B12 NO TECIDO HEMATOPOIÉTICO

Daniel Avila  Ramalho; Letícia Mello Matos

doi:10.51161/rems/2710

CONSEQUÊNCIAS DA INGESTÃO DEFICITÁRIA DA VITAMINA B12 NO TECIDO HEMATOPOIÉTICO

Autores

Daniel Avila Ramalho
Letícia Mello Matos

DOI:

https://doi.org/10.51161/rems/2710

Palavras-chave:

INGESTÃO DA VITAMINA B12, TECIDO HEMATOPOIÉTICO, VITAMINA B12

Resumo

Introdução: Também conhecida como Cobalamina, a vitamina B12 desempenha atividades indispensáveis no corpo, como manutenção da cognição e prevenção à degeneração celular de células nervosas. Sobre a conformidade entre o tecido hematopoiético e a Cobalamina, o papel da vitamina B12 refere-se à produção eritrocitária e manutenção dos níveis férricos do organismo, agindo, portanto, na prevenção contra patologias como anemias. Objetivo: Essa revisão de literatura tem por objetivo elucidar danos decorrentes da ingestão deficitária da Cobalamina no tecido hematopoiético. Material e métodos: Trata-se de uma revisão bibliográfica acerca dos efeitos da ingestão deficitária da vitamina B12 no tecido hematopoiético. Pesquisou-se nas bases de dados PubMed e Scielo os termos: “vitamina B12”, “tecido hematopoiético” e “ingestão da vitamina B12”, além dos respectivos em inglês. Resultados: A deficiência de vitamina B12 leva a diversos transtornos hematológicos, neurológicos e cardiovasculares. Isso se deve à sua interferência no metabolismo de homocisteína, aminoácido presente no plasma sanguíneo, e nas reações de metilação do organismo, importantes para a regulação da expressão gênica e, consequentemente, diferenciação celular e formação tecidual. Tais interferências são importantes para o funcionamento adequado do tecido hematopoiético, essencial para a produção dos eritrócitos, cuja deficiência leva a transtornos hematológicos. As principais hemopatologias relacionadas à ingestão defasada de Cobalamina, por sua vez, são as anemias megaloblásticas, cuja sintomatologia engloba fraqueza, palidez, cefaleia e irritabilidade. O tratamento dessas anemias consiste em injeções de vitamina B12 e ácido fólico, necessárias para o funcionamento do tecido hematopoiético, e na suplementação de vitamina C, importante para a absorção de ferro. Portanto, é necessária alimentação rica em Cobalamina, cujos alimentos com maiores concentrações são de origem animal. Vale ressaltar que é essencial àqueles que fazem dietas vegetarianas ou veganas a suplementação dessa vitamina ou a ingestão de levedura nutricional, única fonte de vitamina B12 que não é de origem animal. Conclusão: Assim, a ingestão de vitamina B12 é importante para o organismo visto que sua deficiência leva a diversos transtornos graves que dificultam a manutenção da vida. Logo, abordagem clínica e diagnóstica, além de detalhes terapêuticos e suplementação cobalamínica, são indispensáveis para a garantia da qualidade de vida da população.

Publicado

2021-12-13

Como Citar

Ramalho, D. A. ., & Letícia Mello Matos. (2021). CONSEQUÊNCIAS DA INGESTÃO DEFICITÁRIA DA VITAMINA B12 NO TECIDO HEMATOPOIÉTICO. Revista Multidisciplinar Em Saúde, 2(4), 2. https://doi.org/10.51161/rems/2710

Baixar Citação

Edição

v. 2 n. 4 (2021)

Seção

I Congresso On-line Nacional de Histologia e Embriologia Humana

Licença

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

O conteúdo desta revista foi migrado para https://editoraintegrar.com.br

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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                                                         SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[1], , null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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