CARCINOMA UROTELIAL EM FELINOS: A IMPORTÂNCIA DA AVALIAÇÃO DE COMPONENTES CELULARES EM SEDIMENTO URINÁRIO – RELATO DE CASO

Maurício  Wilmsen; Cristian André  Bertuzzi; Caian Silva  Correa; Jaqueline  Mombach; Pâmela Padovani  Martins

doi:10.51161/rems/2637

CARCINOMA UROTELIAL EM FELINOS: A IMPORTÂNCIA DA AVALIAÇÃO DE COMPONENTES CELULARES EM SEDIMENTO URINÁRIO – RELATO DE CASO

Autores

Maurício Wilmsen
Cristian André Bertuzzi
Caian Silva Correa
Jaqueline Mombach
Pâmela Padovani Martins

DOI:

https://doi.org/10.51161/rems/2637

Palavras-chave:

ANISOCITOSE, ANISOCARIOSE, CISTOCENTESE, CRITÉRIOS DE MALIGNIDADE, NEOPLASIA

Resumo

Introdução: As neoplasias da bexiga são majoritariamente malignas, sendo que cerca de 85 % correspondem aos carcinomas uroteliais (CUT), anteriormente denominado como carcinomas das células de transição (CCT). O carcinoma urotelial é a neoplasia mais comum do trato urinário, com alta prevalência ocorrendo em região de trígono vesical, o qual é composto por epitélio transicional anaplásico a pleomórfico. O diagnóstico é baseado em exames de imagem e também através do exame de urinálise, mais especificamente a avaliação do sedimento urinário. A avaliação da composição ciotológica da urina e a associação com a neoplasia pode ser realizada através da alteração morfológica das células ou através da verificação de critérios de malignidade celular. Objetivo: demonstrar a relevância da avaliação do sedimento urinário como ferramenta diagnóstica para neoplasias do trato urinário inferior. Material e métodos: Foi atendido, na Clínica Veterinária Universitária da Pontifícia Universidade Católica do Paraná - campus Toledo, um felino, macho, sem raça definida, 16 anos de idade, com histórico de apatia, anorexia, vômito e hematúria com evolução de dois dias. Segundo o tutor, o animal havia realizado procedimento cirúrgico há 6 meses para retirada de um carcinoma utorelial. Foram coletadas duas amostras de urina uma por cistocentese e outra por cateterização, a fim de avaliar os componentes celulares presentes na amostra. Na sedimentoscopia urinária foram visualizados tipos celulares neoplásicos nas duas amostras. Entretanto, na amostra realizada através de sondagem uretral (esfoliação) foram visualizadas em maior numero, células com alterações morfológicas. Resultados: na microscopia, foram observadas células epiteliais neoplásicas pleomórficas com nucléolo evidente, marcante anisocitose e anisocariose e presença de células multinucleadas. As características das células do sedimento urinário puderam confirmar a recidiva do carcinoma urotelial juntamente com as características dos exames de imagem. Conclusão: O exame do sedimento se apresenta como uma técnica segura, rápida e pouco invasiva na contribuição para o diangóstico dos carcinomas uretrais. Além disso, o exame de urina e a esfoliação durante a sondagem podem ser enquadrados como métodos de triagem no diagnóstico desse tipo de neoplasia.

Publicado

2021-12-01

Como Citar

Wilmsen, M. ., Bertuzzi, C. A. ., Correa, C. S. ., Mombach, J. ., & Martins, P. P. . (2021). CARCINOMA UROTELIAL EM FELINOS: A IMPORTÂNCIA DA AVALIAÇÃO DE COMPONENTES CELULARES EM SEDIMENTO URINÁRIO – RELATO DE CASO. Revista Multidisciplinar Em Saúde, 2(3), 16. https://doi.org/10.51161/rems/2637

Baixar Citação

Edição

v. 2 n. 3 (2021)

Seção

I Congresso Nacional On-line de Biologia Celular e Estrutural

Licença

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

O conteúdo desta revista foi migrado para https://editoraintegrar.com.br

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
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                                                            ArticleSearchDAO.getPhraseResults(Object:Journal, Array[1], null, null, , 500, 1) % line  201, file: SubmissionSearch.inc.php
                                                         SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[1], , null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php