EXPOSIÇÃO AMBIENTAL E OCUPACIONAL E O DESENVOLVIMENTO DA ARTRITE REUMATOIDE: REVISÃO NARRATIVA

Autores

  • Nyvea Gabriella de Camargo Monteiro
  • Liziane Cristina De Almeida Arruda
  • Milla Theresa De Campos Assami
  • Cristhiane A. Leite Da Silva

DOI:

https://doi.org/10.51161/rems/1984

Palavras-chave:

ARTRITE REUMATÓIDE, RISCOS AMBIENTAIS, RISCOS OCUPACIONAIS

Resumo

Introdução: Artrite Reumatoide (AR) é uma doença inflamatória sistêmica, crônica e degenerativa, caracterizada  pelo comprometimento da membrana sinovial das articulações periféricas que levam à destruição e limitação funcional e atinge aproximadamente 0,5 a 1% da população mundial. O grande marco da AR é seu potencial de destruir articulações, causando deformidades e limitações. A fisiopatologia da doença, ainda não está completamente elucidada, porém, é sabido que se estabelece uma vez combinados fatores genéticos, ambientais e ocupacionais, determinando o aparecimento do quadro clínico. Objetivos: Analisar a influência da exposição a fatores ambientais e ocupacionais no desenvolvimento da AR. Material e métodos: Estudo produzido através de uma revisão narrativa de literatura, utilizando-se bases de dados: Biblioteca Virtual em Saúde, Scielo, LILACS e Pubmed; entre outubro de 2020 e maio de 2021. Os descritores utilizados para a busca dos artigos foram os Descritores em Ciências da Saúde (DeCS): “Artrite reumatóide”, “Riscos Ambientais”, “Riscos Ocupacionais”. Ao todo, 62 artigos relevantes foram encontrados, possibilitando a discussão sobre o assunto. Resultados: O tabagismo tem sido amplamente estudado e foi comprovado que seu uso possui relação com o desenvolvimento e o rigor da patologia, resultados de pesquisas sugerem que o tabagismo dobra a chance de um indivíduo desenvolver AR ao longo da vida. Outros fatores de risco ambientais também relacionados são obesidade, baixos níveis séricos de vitamina D, doenças inflamatórias intestinais, infecções por certos microrganismos como Proteus mirabillis, vírus Epstein-Barr vírus, sexo feminino e tipo de dieta. Já os fatores ocupacionais ainda não são tão explorados, porém evidências sugerem relação entre a exposição à sílica e a AR. Outras substâncias como asbesto, amianto, óleo mineral e pó têxtil também foram relacionadas Conclusão: Observou-se que o fumo e a sílica são os fatores de exposição mais bem estudados, estando associados ao desenvolvimento e a um pior prognóstico da AR. Pesquisas adicionais permitirão uma compreensão completa dos fatores ambientais e ocupacionais que possa levar a intervenções preventivas para a AR afim de minimizar os riscos e possibilitar melhor qualidade de vida para os pacientes. Ademais, auxiliar a elaboração de políticas públicas com medidas que promovam a conscientização da população.

Publicado

2021-09-14

Como Citar

Monteiro, N. G. de C. ., Arruda, L. C. D. A. ., Assami, M. T. D. C. ., & Silva, C. A. L. D. . (2021). EXPOSIÇÃO AMBIENTAL E OCUPACIONAL E O DESENVOLVIMENTO DA ARTRITE REUMATOIDE: REVISÃO NARRATIVA. Revista Multidisciplinar Em Saúde, 2(3), 128. https://doi.org/10.51161/rems/1984

Edição

v. 2 n. 3 (2021)

Seção

II Congresso Brasileiro de Saúde On-line

Licença

Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

O conteúdo desta revista foi migrado para https://editoraintegrar.com.br

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php