ÁCIDO ÚRICO COMO FATOR DE RISCO PARA DOENÇAS CARDIOVASCULARES: REVISÃO INTEGRATIVA

Autores

  • Rosane Silva Caldas
  • Pedro Gustavo Oliveira de Carvalho
  • Maria Daniella Roseno Arrais

Palavras-chave:

Ácido Úrico, Hiperuricemia, Cardiovascular, Cardiometabólicas

Resumo

Introdução: O ácido úrico sérico (AUS) é o produto final que ocorre a partir da enzima xantina oxidase durante o metabolismo das purinas, sendo produzido pelo fígado a partir dos ácidos nucléicos e excretado pelos rins. O aumento da produção do AUS desencadeia a hiperuricemia, formando pequenos cristais. Objetivo: investigar os níveis de ácido úrico sérico associados ao fator de risco de doenças cardiovasculares. Materiais e Métodos: Foi realizada uma pesquisa integrativa dos estudos e materiais elaborados e publicados, avaliados e selecionados através das bases: LILACS e SciELO. Utilizando os descritores: “Hiperuricemia”, “Ácido úrico” e “Doenças Cardiovasculares”, considerando os critérios de inclusão, artigos disponíveis, em português, inglês e espanhol com ano de publicação a partir de 2010 até setembro de 2019 e de exclusão artigos duplicados, revisões sistemáticas e integrativas incompletas sem estarem disponíveis na plataforma com acesso gratuito. Resultados e Discussão: Foram achados diversos estudos sobre o AUS, como fator de doenças cardiovasculares, cardiometabólicas, relacionando também a obesidade e sedentarismo, com ajuda dos parâmetros do IMC, HDL, exames bioquímicos, acompanhamento da glicemia e hipertensão, entre outros métodos utilizados que influenciam neste processo. Conclusão: De acordo com os estudos realizados, o AUS é relacionado como elemento para os riscos cardiovasculares, desencadeando a Hiperuricemia. Certamente, após alguns trabalhos dos quais aplicaram o AUS como um exame de auxílio para detectar estas doenças em sua fase inicial, podendo ser introduzida nos hospitais e clínicas, para melhor a qualidade de vida dos grupos mais afetados, dos quais encontrados neste estudo foram as mulheres e adolescentes obesos. Contudo, são necessários mais estudos que expliquem esta relação, como também sobre o sexo e as idades que favorecem ao aumento do AUS e as doenças cardiovasculares.

Publicado

2020-07-01

Como Citar

Silva Caldas, R. ., Oliveira de Carvalho, P. G. ., & Roseno Arrais, M. D. (2020). ÁCIDO ÚRICO COMO FATOR DE RISCO PARA DOENÇAS CARDIOVASCULARES: REVISÃO INTEGRATIVA. Revista Multidisciplinar Em Saúde, 1(2), 25. Recuperado de http://editoraime.com.br/revistas/rems/article/view/185
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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
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