MONITORAMENTO DE ISOLADOS DE PSEUDOMONAS SPP. E ACINETOBACTER SPP. RECUPERADOS NO HOSPITAL UNIVERSITÁRIO DE LONDRINA EM UM PERÍODO DE CINCO ANOS

Autores

  • Larissa Dos Santos Fávaro
  • Suelen Balero De Paula-Petroli
  • Renato Eiki Radoski
  • Floristher Elaine Carrara-Marroni
  • Emerson José Venâncio

DOI:

https://doi.org/10.51161/rems/1454

Palavras-chave:

ACINETOBACTER SPP., EPIDEMIOLOGIA, PSEUDOMONAS SPP., RESISTÊNCIA AOS ANTIMICROBIANOS

Resumo

Introdução: Pseudomonas spp. e Acinetobacter spp. são importantes patógenos hospitalares responsáveis por infecções de difícil tratamento e apresentam alta capacidade de adquirir novos determinantes de resistência. O monitoramento das taxas de resistência permite o conhecimento da realidade epidemiológica da instituição, elaboração adequada de estratégias de prevenção e controle de infecções, norteando as terapias empíricas. Objetivo: Determinar o perfil dos isolados clínicos de Pseudomonas spp. e Acinetobacter spp. recuperados no Hospital Universitário (HU) de Londrina no período de janeiro de 2016 a dezembro de 2020. Material e Métodos: Foram analisados dados referentes às culturas positivas para Pseudomonas spp. e Acinetobacter spp. quanto ao sexo do paciente, tipo de amostra biológica, setor de internação e perfil de sensibilidade aos antimicrobianos. Apenas uma amostra por paciente foi incluída no estudo. Resultados: Um total de 1651 isolados de Pseudomonas spp. e 1853 de Acinetobacter spp. foram incluídos no estudo. A maioria dos isolados (63,8% e 64,2%) foram recuperados de pacientes do sexo masculino internados nas Unidades de Tratamento Intensivo (35,8% e 51,4%), Unidades de Tratamento de Queimados (7,9% e 11,8%) e Enfermaria Masculina (8,1% e 7,0%), respectivamente. Secreção traqueal (38,2% e 52,0%), urina (23,4% e 11,2%), swab de vigilância (7,5% e 15,5%) e tecido (10,4% e 9,4%) foram às amostras clínicas com maior frequência de isolamento destes microrganismos. Taxas elevadas de resistência foram verificadas aos carbapenêmicos (35,6%; 83,6% - Imipenem/35,4%; 82,9% - Meropenem), fluoroquinolonas (29,4%; 59,3% - Ciprofloxacin/22,6%; 55,9% - Levofloxacin), cefalosporinas (24,8%; 62,1% - Ceftazidima/27,1%; 60,9% - Cefepime/59,3% - Ceftriaxona) e aminoglicosídeos (26,0%; 46,4% - Gentamicina/20,4%; 52,8% - Amicacina). As polimixinas apresentaram altas taxas de sensibilidade (50,2%; 30,1% - Polimixina B/47,2%; 39,7% - Colistina). Conclusão: As taxas de resistência observadas demonstram as limitações terapêuticas em infecções causadas por estes patógenos no HU, enfatizando a importância no monitoramento da resistência e adequação de estratégias efetivas de prevenção e controle de infecções.

Publicado

2021-07-28

Como Citar

Fávaro, L. D. S. ., Paula-Petroli, S. B. D. ., Radoski, R. E. ., Carrara-Marroni, F. E., & Venâncio, E. J. . (2021). MONITORAMENTO DE ISOLADOS DE PSEUDOMONAS SPP. E ACINETOBACTER SPP. RECUPERADOS NO HOSPITAL UNIVERSITÁRIO DE LONDRINA EM UM PERÍODO DE CINCO ANOS. Revista Multidisciplinar Em Saúde, 2(3), 50. https://doi.org/10.51161/rems/1454

Edição

Seção

II Congresso Brasileiro de Saúde On-line

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

Deprecated: Function get_magic_quotes_runtime() is deprecated in /home/editoraime/public_html/revistas/lib/pkp/lib/vendor/adodb/adodb-php/adodb.inc.php on line 2067
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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php
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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php
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                                                            ArticleSearchDAO.getPhraseResults(Object:Journal, Array[1], null, null, , 500, 1) % line  201, file: SubmissionSearch.inc.php
                                                         SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[1], , null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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