ANTIBIÓTICOS E MECANISMOS DE RESISTÊNCIA BACTERIANA: UMA QUESTÃO DE SAÚDE PÚBLICA.

Jéssica Wedna da Silva  Alves

doi:10.51161/rems/1195

ANTIBIÓTICOS E MECANISMOS DE RESISTÊNCIA BACTERIANA: UMA QUESTÃO DE SAÚDE PÚBLICA.

Autores

Jéssica Wedna da Silva Alves

DOI:

https://doi.org/10.51161/rems/1195

Palavras-chave:

ANTIBIÓTICOS, MECANISMOS DE RESISTÊNCIA BACTERIANA, SAÚDE PÚBLICA

Resumo

Introdução: A descoberta dos antibióticos é um marco na história da saúde mundial, o emprego desses fármacos possibilitou uma revolução no tratamento de infecções e permitiu significativa redução na taxa de mortalidade. No entanto, nos últimos anos devido ao uso indiscriminado destes medicamentos, surgiu a resistência bacteriana frente ao tratamento com estas drogas, o que é considerado um grave problema de saúde pública e que preocupa cientistas, profissionais de saúde e a população de maneira geral. Objetivos: Registrar a importância dos antibióticos no tratamento de infecções, demonstrar os tipos de mecanismos utilizados pelas bactérias no desenvolvimento da resistência bacteriana e mostrar a resistência bacteriana como um problema de saúde pública. Material e métodos: Este estudo foi realizado com base em estudos publicados em revistas e bases de dados online como Pubmed, Scielo e Biblioteca Virtual de Saúde (BVS) nos últimos cinco anos, que correspondem aos anos de 2017 ao ano de 2021. Resultados: Os antibióticos são uma das classes mais prescritas, o que já leva a uma reflexão sobre a real necessidade da prescrição. As possibilidades de mecanismo de ação desses fármacos são muito variadas e o mesmo também é válido para os tipos de desenvolvimento de resistência. Observou-se que os mecanismos mais comuns são a mudança na permeabilidade da membrana celular, que vai alterar a entrada ou permanência do antibiótico dentro da célula, obtenção de capacidade de degradação ou inativação do antibiótico, ou o aparecimento de mutação que altere o alvo, impossibilitando assim que a bactéria seja afetada. Conclusão: Diante da análise dos dados observados nos estudos, podemos inferir que o uso indiscriminado de antibióticos representa um risco à saúde pública mundial e que a resistência bacteriana é um problema que afeta diretamente a população, desde a saúde propriamente dita a economia por comprometer a produtividade. Cabendo aos órgãos públicos ações de conscientização sobre o uso correto desses medicamentos, tanto pelos profissionais de saúde quanto pela população, bem como o incentivo a fiscalizações mais frequentes quanto ao cumprimento das legislações já existentes a respeito da venda desses medicamentos, para que possamos conter esse avanço.

Publicado

2021-06-12

Como Citar

Alves, J. W. da S. (2021). ANTIBIÓTICOS E MECANISMOS DE RESISTÊNCIA BACTERIANA: UMA QUESTÃO DE SAÚDE PÚBLICA. Revista Multidisciplinar Em Saúde, 2(2), 38. https://doi.org/10.51161/rems/1195

Baixar Citação

Edição

v. 2 n. 2 (2021): Edição Especial: Anais de Eventos

Seção

Anais do I Congresso Nacional de Microbiologia Clínica On-Line

Licença

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

O conteúdo desta revista foi migrado para https://editoraintegrar.com.br

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
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                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php