USO RACIONAL DE Hypericum perforatum: UMA REVISÃO BIBLIOGRÁFICA

Autores

  • Mayara Pires Evaristo
  • Juliana Carvalho Ribeiro

DOI:

https://doi.org/10.51161/rems/1037

Palavras-chave:

Hypericum perforatum, hipérico, erva de são joão

Resumo

Introdução: Desde as antigas civilizações relata-se o uso de plantas para fins medicinais. No entanto, com o surgimento do medicamento sintético o interesse por pesquisas com plantas medicinais estagnou-se temporariamente, mas atualmente é o foco de muitos estudos, considerando que o uso de plantas medicinais passou a ser classificado como Prática Integrativa e Complementar em Saúde (PICS). Dentre as plantas de interesse em ser usada para fins medicinais, o hipérico (Hipericum perforatum), também conhecido como erva de são joão, é uma planta medicinal importante em função das suas diversas atividades farmacológicas. No entanto, muitas pessoas acreditam na errônea frase “o que é natural não faz mal” e o hipérico é um exemplo de planta medicinal que apresenta reações adversas e interações medicamentosas, devendo ser usado com cautela. Objetivo: Abordar as principais indicações, interações medicamentosas e reações adversas relacionadas ao uso do hipérico, evidenciando seu uso racional. Material e métodos: Realizou-se uma revisão bibliográfica de literatura, baseada em trabalhos científicos que abortam as palavras-chave em questão. Foram realizadas consultas nas bases de dados de acesso livre na internet como Scielo, Google Acadêmico, livros e e-books disponíveis na biblioteca da UNIFAE, no período de fevereiro a outubro de 2020. Após a coleta de dados estes foram tabulados, construiu-se tabelas e por fim um artigo científico atendendo ao objetivo proposto. Resultados: Dentre as diversas indicações, a literatura consultada destaca suas atividades farmacológicas como antiviral, antimicrobiano, antitumoral, antifúngico, antioxidante e anti-inflamatório. Porém, o grande destaque é relatado em função do efeito antidepressivo, utilizado principalmente no tratamento de depressão unipolar leve e moderada, sendo também promissor para casos de depressão grave. Entretanto, relata-se efeitos adversos como irritações gastrointestinais, reações alérgicas, fadiga e agitação. Recomenda-se, ainda, alguns cuidados com o sol durante o uso do medicamento e a atenção diante de algumas interações medicamentosas, diminuindo a eficácia de anticoncepcionais, varfarina, ciclosporina, digoxina, teofilina e anticonvulsivantes e causando sinergismo com inibidores da receptação de serotonina. Conclusão: Analisando estes dados, observa-se que o hipérico deve ser usado com cautela e sob prescrição médica pois apresenta reações adversas e interações medicamentosas relevantes. Este trabalho reforça a necessidade de orientar a população quanto ao uso racional de plantas medicinais e medicamentos fitoterápicos para que possam ser utilizados com bons resultados econômicos e de melhoria da saúde da população, sendo base para estudos futuros.

Publicado

2021-04-29

Como Citar

Evaristo, M. P., & Ribeiro, J. C. (2021). USO RACIONAL DE Hypericum perforatum: UMA REVISÃO BIBLIOGRÁFICA. Revista Multidisciplinar Em Saúde, 2(1), 25. https://doi.org/10.51161/rems/1037

Edição

Seção

Anais do Congresso Brasileiro de Ciências Farmacêuticas On-line
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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php
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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php
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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php
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   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php
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                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php
                                                                  ADOConnection.CacheExecute(3600, SELECT 				o.submission_id, 				MAX(s.context_id) AS journal_id, 				MAX(i.date_published) AS i_pub, 				MAX(p.date_published) A..., Array[2]) % line  132, file: DAO.inc.php
                                                               DAO.retrieveCached(SELECT 				o.submission_id, 				MAX(s.context_id) AS journal_id, 				MAX(i.date_published) AS i_pub, 				MAX(p.date_published) A..., Array[2], 3600) % line   91, file: ArticleSearchDAO.inc.php
                                                            ArticleSearchDAO.getPhraseResults(Object:Journal, Array[1], null, null, , 500, 1) % line  201, file: SubmissionSearch.inc.php
                                                         SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[1], , null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1267, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6781613650b432_13896783(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  292, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php