INTRODUÇÃO: Pacientes com COVID-19 podem ter graves consequências de curto e longo prazo para os indivíduos sendo necessárias medidas preventivas de saúde que possam reduzir o risco de infecção, progressão e gravidade da doença. Com isso, surgiu o papel da vitamina D como uma possível forma de prevenção de infecções respiratórias agudas. OBJETIVOS: Desenvolver uma revisão de literatura a fim de discutir o possível papel da vitamina D na redução do risco de COVID-19. MATERIAL E MÉTODOS: Estudo do tipo revisão narrativa de literatura, cuja pesquisa foi realizada com base de dados no Scientific Electronic Library Online (SciELO) e no PubMed Central (PMC). RESULTADOS: Estudos de reposição de vitamina D mostraram que esta melhora a imunidade inata (resposta imediata dos macrófagos aos vírus e bactérias invasores nas membranas mucosa, inibição direta com replicação viral ou com formas antiinflamatórias ou imunomoduladoras ), reduzindo assim a incidência e gravidade das infecções respiratórias agudas. A deficiência de vitamina D é mais comum em grupos de idade avançada, fumantes, obesos e em pacientes com doenças crônicas como diabetes, hipertensão. Os grupos de alto risco que apresentam mais complicações e maior mortalidade no COVID-19 coincidem com os grupos que apresentam alta incidência de deficiência de vitamina D. No entanto, ainda não há evidências suficientes sobre a associação entre os níveis de vitamina D e a gravidade e mortalidade da COVID-19. CONCLUSÃO: A discussão aponta para a necessidade e importância de ensaios clínicos randomizados e estudos de corte para compreender melhor o mecanismo e como a Vitamina D age a longo prazo.
Publicado
2021-04-24
Como Citar
Silva, L. F. D. C. ., & Weber, E. P. (2021). O ESTUDO DA SUPLEMENTAÇÃO DE VITAMINA D DURANTE A PANDEMIA DO VÍRUS SARS-COV-2: UMA REVISÃO DE LITERATURA. Revista Multidisciplinar Em Saúde, 2(2), 65. https://doi.org/10.51161/rems/1008
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